Each motor is different. But to help you out a bit, I'm using a Kenji ecu, stock ITR motor right now, running -15 degrees most of my RPM range, minus the midrange, -5 degree at WOT.
My vtec is setup at 4600 rpms, that what the motor likes. I've seen from 5200 to 5500 rpms, again, each motor is different.
Don't forget the header, something like the SMSP style header or Compptech Race header, needs alot of fuel, hence bigger injectors and more tuning.
-Bert