Here's a dyno chart of a VR6 with these mods: Big Valve Head 41mm Intake & Exhasut Valves - Lightened Valve Retainers - Schrick Springs - Ported and Polished - TT 2.5 Exhaust - Schrick 268 Cams - Schrick VGI - PRM Intake
I will be honest. I don't really know anything about the VR6, but I did some research. Here's the page I found the dyno charts on.
http://vr6dyno.cjb.net/
That should give you some ideas on what you want to do for what amount of power. I would also say, hold off on the big wheels if you're really looking for enhanced performance.