wow, a bit angry and at the wrong people...
anyhow, rotary motors will have more issue adapting to fuel containing ethanol just because of the fuel's burn rate. A rotary has a very short period of duration for combustion (typically referred to as constant volume combustion...think of dwell) in comparions to a piston motor.

I see you also lost, probably 2-3 mpg (guessing tank size). Right?

I don't know why Mazda has issued the warning for rotary motors, be it fuel system, the engine internals themselves or just because the motor will have issues running (idling could become a PITA). Anyone know more on the bulletin, as I'm intersted.