I have a set on the ONE right now, and I love them. They are nothing like the previous Dunlops. I swore I would never run another Dunlop again, but these tires kick ass.

They dont slide as much as the Pilot Powers, and give you better feed back. They seem to get to operating temperature prety quick (in the current weather conditions). Compared to the Pilot Powers, they have a broader operating temperature. Where the Pilot Power would over heat and grease up, the Qualifier still holds tight.
The Profile on the Pilot Power is alittle rounder then on the Qualifier. Despite being called a 190/50-17 the side wall is alittle taller. The Qualifier feels alot like the Pirelli Diablo Corsa, and anyone who knows me knows I love the Corsa. I cant comment on tire wear yet, but it seems to be on par with the other high end sport bike rubber currently on the market.

What it's going to come down to is what you feel comfortable on. Alot of the slower guys live by the Pilot Power. (Ouch, did I just say that?? LOL )