I've been hearing that dealers will replace struts that clunk. Something like that with toe, you'd hafta take it in and ask.

As far as safety issue, not really. Ride quality, probably not an issue either. But if the toe is out pretty far you'll get abnormal wear on that tire (simple analogy would be dragging the tire sideways while it moves forwards), which can cause a problem down the road as it wears faster than the other side.